WebBD GolgiPlug™ Protein Transport Inhibitor (containing Brefeldin A) Enhance the detectability of cytokine-producing cells with immunofluorescent staining and flow cytometric analysis Supplier: BD 555029 Catalog No. BDB555029 $70.00 / Each of 1 Qty Check Availability Add to cart Description Specifications Customers who viewed this item also … WebMay 15, 2005 · Virus-specific CD8(+) T cells produce IFN-gamma after Ag contact and, in the absence of this cytokine, the host often cannot eradicate infection. However, our ability to identify cells that are actively expressing this critical effector function in vivo is limited, because the protein is rapidly sec …
Brefeldin A: Uses, Interactions, Mechanism of Action - DrugBank
WebBrefeldin A is an inhibitor of intracellular protein transport. Incubation of cells in culture with Brefeldin A leads to blockade of protein transport to the Golgi complex (GC) and … Brefeldin A is a lactone antiviral produced by the fungus Penicillium brefeldianum. Brefeldin A inhibits protein transport from the endoplasmic reticulum to the golgi complex indirectly by preventing association of COP-I coat to the Golgi membrane. Brefeldin A was initially isolated with hopes to … See more The compound gets its name from a species of anamorph fungus of the Penicillium genus known as Eupenicillium brefeldianum, though it is found in a variety of species that span several genera. It was first … See more In mammalian and yeast cells, the main target of brefeldin A appears to be a guanine nucleotide exchange factor (GEF) called GBF1. GBF1 is a member of the Arf family of GEFs which are recruited to membranes of the Golgi. It is responsible for the regulation of See more • Unfolded protein response • Endoplasmic reticulum stress response (ER stress) See more Brefeldin A is found naturally as a white to off-white crystalline solid. It forms a clear colorless solution when dissolved. It is soluble in methanol (10 mg/mL), ethanol (5 mg/mL), See more The toxological effects of brefeldin A have not been studied extensively yet. Some animal LD50 values have been reported including 250 … See more • Klausner RD, Donaldson JG, Lippincott-Schwartz J (March 1992). "Brefeldin A: insights into the control of membrane traffic and organelle structure" See more red sox news and rumors today 202
Molecules Free Full-Text Brefeldin A Reduces Anchorage …
WebCell Activation Cocktail (with Brefeldin A) is composed of PMA, ionomycin, and Brefeldin A in DMSO (500X). Concentration Each vial of this cocktail contains phorbol-12-myristate … WebBrefeldin A: deciphering an enigmatic inhibitor of secretion. Brefeldin A: deciphering an enigmatic inhibitor of secretion Plant Physiol. 2002 Nov;130(3):1102-8. doi: 10.1104/pp.011569. Authors Andreas Nebenführ 1 , Christophe Ritzenthaler, David G Robinson. Affiliation 1 Department of ... WebWhether it's raining, snowing, sleeting, or hailing, our live precipitation map can help you prepare and stay dry. rick o\u0027shea book club