WebCisplatin DRUG NAME: Cisplatin SYNONYM: CDDP ,1 cis-Diamminedichloroplatinum 2dichlorodiammineplatinum(II) 3 Patinum II DDP 4. COMMON TRADE NAME: … Cisplatin is a chemotherapy medication used to treat a number of cancers. These include testicular cancer, ovarian cancer, cervical cancer, bladder cancer, head and neck cancer, esophageal cancer, lung cancer, mesothelioma, brain tumors and neuroblastoma. It is given by injection into a vein. Common side … See more Cisplatin is administered intravenously as short-term infusion in normal saline for treatment of solid and haematological malignancies. It is used to treat various types of cancers, including sarcomas, some See more Cisplatin is the square planar coordination complex cis-[Pt(NH3)2Cl2]. The prefix cis indicates the cis isomer in which two similar ligands are in … See more Syntheses of cisplatin start from potassium tetrachloroplatinate. Several procedures are available. One obstacle is the facile formation of Magnus's green salt (MGS), which has the same empirical formula as cisplatin. The traditional way to avoid MGS involves the … See more Cisplatin has a number of side effects that can limit its use: • Nephrotoxicity (kidney damage) is the primary dose … See more Cisplatin interferes with DNA replication, which kills the fastest proliferating cells, which in theory are cancerous. Following administration, one … See more The compound cis-[Pt(NH3)2Cl2] was first described by Italian chemist Michele Peyrone in 1845, and known for a long time as Peyrone's … See more Cisplatin has been studied with Auger therapy to increase the therapeutic effects of cisplatin, without increasing normal tissue toxicities. See more
PRODUCT INFORMATION – DBL CISPLATIN …
http://www.bccancer.bc.ca/drug-database-site/Drug%20Index/Cisplatin_monograph.pdf WebOct 22, 2024 · Cisplatin plus 5-fluorouracil (5-FU) given every 3 weeks during radiation. For cervical cancer that has spread or come back after treatment. Chemo may be used to treat cervical cancer that has spread to other organs and tissues (advanced cervical cancer). It can also be helpful when cervical cancer comes back after treatment with … share weight
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WebFeb 16, 2024 · Generic name: cisplatin [ sis-PLA-tin ] Drug class: Alkylating agents. Medically reviewed by Drugs.com on Feb 16, 2024. Written by Cerner Multum. The Platinol brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available. Uses; WebSep 15, 2024 · Cisplatin (cisplatin injection) (cis-diamminedichloroplatinum) is a heavy metal complex containing a central atom of platinum surrounded by two chloride atoms and two ammonia molecules in the cis position. It is a white powder with the molecular formula PtCl 2 H 6 N 2, and a molecular weight of 300.05. WebMar 20, 2024 · Platinum-based anticancer drugs, including cisplatin, carboplatin, oxaliplatin, nedaplatin, and lobaplatin, are heavily applied in chemotherapy regimens. However, the intrinsic or acquired resistance severely limit the clinical application of platinum-based treatment. The underlying mechanisms are incredibly complicated. … share websites