WebJul 9, 2015 · Background: The syncytialization of cytotrophoblast cells to syncytiotrophoblast is central to human placental transport and hormone production. Many techniques for in vitro study of this process have been proposed and new investigators to the field may find the literature in the field daunting. WebFeb 22, 2014 · NK cells do attack self-cells if the level of MHC1 expressed is reduced (e.g. cancer cells). This is why OP is asking why NK cells don't attack the syncytiotrophoblast (that lack MHC1 altogether). The answer lies in the fact that maternal antibodies prevent NK cells from binding to the syncytiotrophoblast.

National Center for Biotechnology Information

WebNov 10, 2015 · Syncytiotrophoblast is the primary barrier regulating the exchange of nutrients and gases between maternal and fetal blood and is the principal site for synthesizing hormones vital for human pregnancy. How trophoblast cells regulate their differentiation into a syncytium is not well understood. WebThe cytotrophoblast is considered to be the trophoblastic stem cell because the layer surrounding the blastocyst remains while daughter cells differentiate and proliferate to function in multiple roles. There are two … iphone 6 wet repair

Cytotrophoblast Britannica

Syncytiotrophoblast (from the Greek 'syn'- "together"; 'cytio'- "of cells"; 'tropho'- "nutrition"; 'blast'- "bud") is the epithelial covering of the highly vascular embryonic placental villi, which invades the wall of the uterus to establish nutrient circulation between the embryo and the mother. It is a … See more It is the outer layer of the trophoblasts and actively invades the uterine wall, during implantation, rupturing maternal capillaries and thus establishing an interface between maternal blood and embryonic extracellular fluid, … See more The syncytiotrophoblast lacks proliferative capacity and instead is maintained by fusion of underlying cytotrophoblast cells. This fusion is … See more • Cytotrophoblast • Intermediate trophoblast • Syncytium See more • Section through embryonic area of Vespertilio murinus to show the formation of the amniotic cavity. • Histopathology of a chorionic villus, … See more • Histology image: 19908loa – Histology Learning System at Boston University - "Female Reproductive System: placental villi" See more WebThe cytotrophoblast, which lines the cavity, forms fingers of proliferating cells extending … WebSyncytiotrophoblast is continuously replenished throughout pregnancy by fusion of underlying progenitor cells called cytotrophoblasts. Dysregulated syncytiotrophoblast formation disrupts the integrity of the placental exchange surface, which can be detrimental to maternal and fetal health. iphone 6 waterproof case lifeproof