Cytoplasmic aconitate hydratase-like
WebJul 12, 2024 · After the discovery in 1967 of plant glyoxysomes, aconitase, one the five enzymes involved in the glyoxylate cycle, was thought to be present in the organelles, and although this was found not to be the case around 25 years ago, it is still suggested in some textbooks and recent scientific articles. Genetic research (including the study of mutants … WebCytoplasmic aconitate hydratase Kind protein Organism Humans Protein. Name UniProt ID; Cytoplasmic aconitate hydratase: P21399: Details: Drug Relations Drug Relations. …
Cytoplasmic aconitate hydratase-like
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WebMay 27, 1998 · AH, aconitate hydratase (EC.4.2.1.3) NAD + –ICDH, NAD +-specific isocitrate dehydrogenase (EC.1.1.1.41) ... Some plants, like Kalanchoe leaves are unable to accumulate large amounts of isocitrate, ... The oxidation of cytoplasmic NAD(P)H when complex I in the electron transport chain is inhibited can be performed by rotenone … WebCytoplasmic aconitate hydratase Synonyms. 4.2.1.3; Aconitase; Citrate hydro-lyase; Ferritin repressor protein; IRE-BP 1; IREB1; Iron regulatory protein 1; Iron-responsive element-binding protein 1; IRP1; Gene Name ACO1 Organism Humans Amino acid …
WebIron and citrate are essential for the metabolism of most organisms, and regulation of iron and citrate biology at both the cellular and systemic levels is critical for normal physiology and survival. Mitochondrial and cytosolic aconitases catalyze the interconversion of citrate and isocitrate, and … WebSep 21, 2008 · Data on the structure, functions, regulation of activity, and expression of cytosolic and mitochondrial aconitate hydratase isoenzymes of mammals are reviewed. The role of aconitate hydratase and structurally similar iron-regulatory protein in maintenance of homeostasis of cell iron is described. Information on modifications of the …
WebThis paper describes the characterization of aconitate hydratase (EC 4.2.1.3) in cytoplasmic and mitochondrial extracts from Ehrlich ascites tumor cells carried by … WebDec 23, 2003 · Nevertheless, little is known regarding the response of aconitase to pro-oxidants within intact mitochondria. In the present study, we provide evidence that aconitase is rapidly inactivated and subsequently reactivated when isolated cardiac mitochondria are treated with H (2)O (2). Reactivation of the enzyme is dependent on the presence of the ...
WebSpecific Function. Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, …
WebSearch Result : 7756 hits. Entry KO len SW-score(margin) bits identity overlap best(all the pill gambleAconitase (aconitate hydratase; EC 4.2.1.3) is an enzyme that catalyses the stereo-specific isomerization of citrate to isocitrate via cis-aconitate in the tricarboxylic acid cycle, a non-redox-active process. • Citric acid • Aconitic acid siddhartha nepalWebAconitase is an iron–sulfur protein that isomerizes citrate to isocitrate through the enzyme-bound intermediate cis -aconitate. The two-step reaction is reversible and involves dehydration followed by hydration. Although citrate is a symmetric molecule, aconitase works specifically on the OAA end of citrate, not the end derived from acetyl ... siddhartha novel pdfWebImmunocytochemistry/ Immunofluorescence: Aconitase 1 Antibody [NBP1-87677] - Staining of human cell line U-2 OS shows localization to cytosol & mitochondria. Antibody staining is shown in green. Immunohistochemistry-Paraffin: Aconitase 1 Antibody [NBP1-87677] - Staining of human duodenum shows strong cytoplasmic positivity in glandular cells. the pill gameplayWebWe show that PP2A-B'γ physically interacts with the cytoplasmic form of aconitase, a central metabolic enzyme functionally connected with mitochondrial respiration, oxidative stress responses and regulation of cell death in plants. Furthermore, PP2A-B'γ impacts ROS homeostasis by controlling the abundance of specific alternative oxidase ... the pill gedarelWebMar 3, 2024 · Area under the receiver operating characteristic curve (AUC) for cytoplasmic aconitate hydratase, argininosuccinate synthase, carbamoylphosphate synthase, fumarylacetoacetase, fructose-1,6-bisphosphatase 1 (FBP1) across cohorts achieved near complete separation (range: 0.94-0.99) of DO and HV. In addition, we show that FBP1, … siddhartha obermenzing homepagesiddhartha new movie