WebFISH. Test Description. Probes: ALK (2p23) Disease (s): Non-small cell lung carcinoma (NSCLC) Clinical Significance. ALK gene rearrangements are found in 3-5% of non-small cell lung carcinoma (NSCLC) and determine likelihood of response to crizotinib (Xalkori®) therapy. Specimen Requirements. Paraffin Block: H&E slide (required) plus paraffin ... WebMay 20, 2012 · Methods: NSCLC patients (N=120) seen at the Cleveland Clinic (CC) who had clinical screening ALK 2p23 FISH (Abbott Molecular) were included in this …
ALK for NSCLC NeoGenomics Laboratories
WebThe ALK (2p23) Proximal, ALK (2p23) Proximal-HS and ALK (2p23) Proximal - XL FISH probes are optimized to detect the genomic region proximal to the ALK breakpoint(s) at 2p23. These reagents are analyte specific reagents. Analytical and performance characteristics are not established. WebLung Cancer Diagnostic Kit. The ALK FISH probe set is designed to detect rearrangements involving portions of the human ALK gene located on chromosome band 2p23.2. The kit contains two differentially labeled Locus Specific Probes (LSP), one covering the 5’ (start) portion of the ALK gene and some adjacent genomic sequence, the other covering ... small creeper farm without cats
ALK Break Apart FISH Probe Kit - CytoTest
WebThe fusion of echinoderm microtubule-associated protein-like 4 (EML4) gene with the ALK gene results from an inversion of chromosome band 2p23. The ALK-EML4 … WebTest Usage. This test detects rearrangements involving the ALK gene (2p23) via fluorescence in situ hybridization (FISH) in formalin-fixed paraffin-embedded (FFPE) non … WebThe Vysis ALK Break Apart FISH probe kit is a qualitative test to detect rearrangements involving the ALK gene in formalin-fixed paraffin embedded non-small cell lung cancer … sompo holdings organization chart