Tov-21g cisplatin

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August undefined, 2024

WebCryptocaryone (CPC) is a bioactive dihydrochalcone derived from Cryptocarya plants, and its antiproliferation was rarely reported, especially for ovarian cancer (OVCA). This study aimed to examine the regulation ability and mechanism of CPC on three histotypes of OVCA cells (SKOV3, TOV-21G, and TOV-112D). In a 24 h MTS assay, CPC showed antiproliferation … WebSep 28, 2024 · When TOV-21G cells were treated with morin and cisplatin simultaneously for 24 h (APP:1; Fig. 2a), there occurred a synergism at low concentrations of cisplatin (3.125–6.25 µM), an additive effect at a medium dose of cisplatin (12.5 µM), and an antagonism at high concentrations of cisplatin (25–50 µM).

Ovarian Cancer Cell Line Panel (OCCP): Clinical Importance of

WebCompound Viability screens Drug sensitivity AUC (Sanger GDSC1) Drug sensitivity AUC (Sanger GDSC2) Drug sensitivity IC50 (Sanger GDSC1) Drug sensitivity IC50 (Sanger GDSC2) Drug sensitivity AUC (CTD^2) Drug sensitivity (PRISM Repurposing Primary Screen) Drug sensitivity AUC (PRISM Repurposing Secondary Screen) Drug sensitivity replicate-level … WebMorin decreases galectin-3 expression and sensitizes ovarian cancer cells to cisplatin. Bieg D; Sypniewski D; Nowak E; et al. See more; Archives of Gynecology and Obstetrics (2024) 298(6) 1181-1194. DOI: 10.1007/s00404-018-4912-4. … 夜イラスト手書き

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WebApr 13, 2024 · In addition, PLGA-PEG-based nanoparticles were used to encapsulate both cisplatin and wortmannin for the treatment of platinum-resistant ovarian cancer. 45 In this combination system, wortmannin, a phosphoinositide 3-kinase inhibitor, can potently block downstream DNA repair pathways that are involved in cisplatin resistance. 46,47 As a … WebThe cells were treated with indicated concentrations of the drugs in indicated periods of time: a TOV-21G and SK-OV-3 cells treated with cisplatin (6.25–100 µM) for 24 h, b TOV-21G cells ... WebApr 7, 2003 · This pathway regulates cisplatin sensitivity and is governed by the coordinate activity of six genes associated with ... (2008 and TOV-21G) did not express FANCD2-L (Fig. 1b, lanes 3, 4 ... b-pass all area ビーパス・オール・エリア vol.14

Morin decreases galectin-3 expres... preview & related info

WebOverview. Name (s) TOV-21G. Tissue Ovary. Cancer Type Ovarian Carcinoma. Tissue Status Tumour. Sample Site Ovary. Cancer Type Details Ovarian Clear Cell Adenocarcinoma (NCIT C40078) GDSC Growth Estimate 3.60 +/- 0.91 (16 replicates) WebMay 11, 2024 · For cisplatin-treated TOV-21G cells, the IC50 value was 77.56 µM, while the same cytotoxic effect was obtained by treating the cells with the two drugs at a cisplatin concentration of 50 µM. A synergistic effect of α-mangostin and cisplatin was also observed on cisplatin-resistant SKOV-3 cells. bpassテストWebMar 21, 2024 · SKOV-3, OVCAR-3, TOV-21G and A2780 cells were exposed to varying concentrations of DIM alone or in combination with cisplatin. Cells were collected, lysed, and about 20 to 80 μg protein was subjected to SDS gel electrophoresis followed by immunoblotting as previously described by our group [ 26 ]. 夜あそび 28 時間

"WebThe TOV-21G xenograft model has been used to investigate ovarian oncology pathways, dual tyrosine kinase inhibitors, cisplatin, IGF-IR inhibitors, etc.). TOV-21G cells are maintained in exponential growth phase under aseptic conditions. Cells are trypsinized and cell count viability is determined using a trypan blue exclusion assay (98% of cell ... " - Tov-21g cisplatin

Tov-21g cisplatin

Analysis of human ovarian cancer cells: viability by XTT assay (a ...

WebIn this study the combination of docetaxel plus cisplatin was considerably more active in vitro than any of the other taxane plus platinum agent ... cisplatin, and carboplatin in seven human ovarian cancer cell lines (CAOV-3, OVCAR-3, SKOV-3, ES-2, OV-90, TOV-112D, and TOV-21G). The IC(50) was defined as the drug concentration required ... WebDuring this sensitization, morin significantly reduces the expression of galectin-3 at the mRNA and protein level, regardless of the presence of cisplatin. Conclusions: Morin sensitizes TOV-21G and SK-OV-3 ovarian cancer cells to cisplatin, what is associated with a decrease of the expression of galectin-3.

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WebJun 23, 2024 · (A) TOV21G, JHOC5, KURAMOCHI, and JHOS2 cells were treated with 0–30 μM of cisplatin and IC20 of ED2-AD101 or vehicle for 72 hours. IC50 was compared using Student’s t-test. (B) TOV21G, JHOC5, KURAMOCHI, and JHOS2 cells were treated with either the designated concentrations of cisplatin and ED2-AD101 or vehicle for 72 hours. Left … WebATCC tov 21g cells lines Tov 21g Cells Lines, supplied by ATCC, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS ... Diindolylmethane suppresses ovarian cancer growth and potentiates the effect of cisplatin in tumor mouse model by targeting signal transducer and activator of transcription 3 (STAT3 ...

WebShulin Li, 1 Yuqi Wu, 1 Jiawei Zhang, 1 Hao Sun, 2 Xiangwei Wang 1 1 Department of Urology & Carson International Cancer Center, Shenzhen University General Hospital & Shenzhen University Clinical Medical Academy Center, Shenzhen University, Shenzhen 518000, People’s Republic of China; 2 Department of Urology & Carson International Cancer … WebSep 28, 2024 · It is demonstrated that morin possess antitumor activity against TOV-21G and SK-OV-3 ovarian cancer cells by reducing cell viability and proliferation as well as increasing the induction of apoptosis. PurposeThis study aimed at evaluating whether morin (a natural flavonoid and a known inhibitor of NF-κB) can sensitize ovarian cancer cells to …

WebJan 1, 2024 · The TOV-21G cells were characterized by a different gene expression profile than that used for the SKOV-3 cells. In TOV-21G cells treated with cisplatin alone, only TP53TG5 and CASPASE-8 were up-regulated, while in presence of rhTRAIL alone or combined with cisplatin, CASPASE-8 and BAX were up-regulated and BCL-2 was down … Webcombination with cisplatin. Cells were collected, lysed, and about 20 to 80 μg protein was subjected to SDS gel electrophoresis followed by immunoblotting as pre-viously described by our group [26]. Nuclear fractionation SKOV-3, OVCAR-3, TOV-21G, or A2780 cells were plated at a density of 1 × 106 in 100 mm culture dishes

WebCisplatin is considered to be the most active platinum agent drug. Neoadjuvant (or induction) chemotherapy can be used for cervical cancer patients with locally advanced disease; this treatment is followed by radical surgery and/or radiation therapy.

WebSep 8, 2024 · Cisplatin-resistant ES2 cells were generated by exposing the parental ES2 cells to increasing doses of cisplatin over a period of 5 months with gradual dose escalations every 3 weeks. Human specimens b-pass all area ビーパス・オール・エリア vol.13Web2 days ago · In addition, PLGA-PEG-based nanoparticles were used to encapsulate both cisplatin and wortmannin for the treatment of platinum-resistant ovarian cancer. 45 In this combination system, wortmannin, a phosphoinositide 3-kinase inhibitor, can potently block downstream DNA repair pathways that are involved in cisplatin resistance. 46,47 As a … bpa xpath の結果を照会できませんでしたWebApr 2, 2024 · Ovarian cancer is the most lethal gynaecological disease in women and, in 2024, there will be approximately 300,000 new diagnoses of ovarian cancer worldwide 1.Despite the improvement in prognosis ... 夜イヴWebTo cite this cell line use: TOV-21G (RRID:CVCL_3613) Comments. Group: Patented cell line. Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Part of: COSMIC cell lines project. Part of: KuDOS 95 cell line panel. Part of: MD Anderson Cell Lines Project. Part of: OCCP ovarian cancer cell line panel. 夜ウエイトWebMay 11, 2024 · demonstrate that treatment of A2780, SKOV-3, and TOV-21G cells with -mangostin in combination with cisplatin can allow a reduction in cisplatin concentration while maintaining the same cytotoxic effect. Ovarian cancer cells release a variable number of exosomes into the microenvironment when exposed to -mangostin and/or cisplatin. bpasとはWebMar 5, 2014 · Suppression of REV7 enhances cisplatin (CDDP) sensitivity in vivo. (a) Growth of inoculated tumors in nude mice with and without systemic CDDP treatment. REV7‐knockdown (shREV7) or control (shCont) ovarian clear cell carcinoma TOV‐21G cells (1 × 10 7) were used in this analysis. 夜いろんな国の言葉WebMar 30, 2024 · We also examined the effects of isolated exosome fractions on normal human cells (NHDF human fibroblast line). In the present study, we demonstrate that treatment of A2780, SKOV-3, and TOV-21G cells with α-mangostin in combination with cisplatin can allow a reduction in cisplatin concentration while maintaining the same … 夜イベント東京